Refractory Osteomyelitis
Osteomyelitis is an infection of bone or bone marrow, usually caused by pyogenic bacteria or mycobacteria. Refractory osteomyelitis is defined as a chronic osteomyelitis that persists or recurs after appropriate interventions have been performed or where acute osteomyelitis has not responded to accepted management techniques.
Osteomyelitis is an accepted indication for Hyperbaric Oxygen treatment and is coverd by Medicare and most insurance. However the medical profession is somewhat unaware of this and the potential benefit in using it early as an adjunctive therapy.
The dose that is commonly recommended is a 90-minute dose, 3 times a day for 2 days, and then twice a day until "under control."
Modalities of HBOT effects on Osteomyelitis
Osteomyelitis is an accepted indication for Hyperbaric Oxygen treatment and is coverd by Medicare and most insurance. However the medical profession is somewhat unaware of this and the potential benefit in using it early as an adjunctive therapy.
The dose that is commonly recommended is a 90-minute dose, 3 times a day for 2 days, and then twice a day until "under control."
Modalities of HBOT effects on Osteomyelitis
- improve leukocyte function
- bacteriostatic and inhibit the growth of anaerobic organisms
- inhibit the production of clostridial alpha-toxin
- inhibit exotoxin to host tissues
- potentiate the action of aminoglycosides antibiotics
- induce angiogenesis, particularly in a hypoxic environment.